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膵臓がん研究

膵臓がんにおける老化細胞除去療法の可能性ーFGFR4阻害剤のBLU9931は増殖と浸潤を抑制するとともに膵臓がん細胞を老化誘導する

Norihiko Sasaki N, Fujiya Gomi , Hisashi Yoshimura, Masami Yamamoto, Yoko Matsuda, Masaki Michishita, Hitoshi Hatakeyama, Yoichi Kawano, Masashi Toyoda, Murray Korc, Toshiyuki Ishiwata. FGFR4 Inhibitor BLU9931 Attenuates Pancreatic Cancer Cell Proliferation and Invasion While Inducing Senescence: Evidence for Senolytic Therapy Potential in Pancreatic Cancer. Cancers (Basel). 2020 Oct 14;12(10):2976. doi: 10.3390/cancers12102976. PMID: 33066597. Cancers | Free Full-Text | FGFR4 Inhibitor BLU9931 Attenuates Pancreatic Cancer Cell Proliferation and Invasion While Inducing Senescence: Evidence for Senolytic Therapy Potential in Pancreatic Cancer (mdpi.com)