組織切片FISH法による研究
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Accelerated telomere shortening in adrenal zona reticularis in patients with prolonged critical illness. Keisuke Nonaka, Kaiyo Takubo, Junko Aida, Yoriko Watai, Akiko Komatsu, Fujiya Gomi, Yuuki Shichi, Yuto Yamazaki, Toshiyuki Ishiwata, Hironobu Sasano, Tomio Arai. Front Endocrinol (Lausanne). 2023 Sep 4;14:1244553. https://www.frontiersin.org/articles/10.3389/fendo.2023.1244553/full
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Telomere lengths in Barrett’s esophagus as a precancerous lesion. Junko Aida, Kaiyo Takubo, Michael Vieth, Horst Neuhaus, Mutsunori Fujiwara, Tomio Arai, Toshiyuki Ishiwata. Esophagus. 2021 Sep 24. doi: 10.1007/s10388-021-00884-4.
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Correlation between Telomere Attrition of Zona Fasciculata and Adrenal Weight Reduction in Older Men. Keisuke Nonaka, Junko Aida, Kaiyo Takubo, Yuto Yamazaki, Xin Gao, Akiko Komatsu, Shoichiro Takakuma, Mototsune Kakizaki, Naoko Inoshita, Toshiyuki Ishiwata, Ja Mun-Chong, Tomio Arai, Hironobu Sasano. J Clin Endocrinol Metab. 2019 Nov 20.
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Correlation between Differentiation of Adrenocortical Zones and Telomere Lengths measured by Q-FISH. Keisuke Nonaka, Junko Aida, Kaiyo Takubo, Yuto Yamazaki, Shoichiro Takakuma, Matotsune Kakizaki, Yoko Matsuda , Naoshi Ishikawa, Toshiyuki Ishiwata, Ja-Mun Chon, Tomio Arai, Hironobu Sasano. J Clin Endocrinol Metab. 2019 Jun 20.
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Quantitative fluorescence in situ hybridization for investigation of telomere length dynamics in the pituitary gland using samples from 128 autopsied patients. Hiraishi N, Terai M, Fujiwara M, Aida J,Izumiyama-Shimomura N, Ishikawa N, Tomita K, Matsuda Y, Arai T, Takubo K, Ishiwata T.Tissue Cell. 2018 Aug;53:1-7.
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Gradual telomere shortening and increasing chromosomal instability among PanIN grades and normal ductal epithelia with and without cancer in the pancreas. Matsuda Y, Ishiwata T, Izumiyama-Shimomura N, Hamayasu H, Fujiwara M, Tomita K, Hiraishi N, Nakamura K, Ishikawa N, Aida J, Takubo K, Arai T. PLoS One 2015; 10: e0117575
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Short telomeres in an oral precancerous lesion: Q-FISH analysis of leukoplakia. Junko Aida, Takanori Kobayashi, Takashi Saku, Masatsune Yamaguchi, Naotaka Shimomura, Ken-ichi Nakamura, Naoshi Ishikawa, Satoshi Maruyama, Jun Cheng, Steven SS Poon, Motoji Sawabe, Tomio Arai, Kaiyo Takubo. J Oral Pathol Med. 2012; 41: 372-378
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Hepatocellular telomere length in biliary atresia measured by Q-FISH. Sanada Y, Aida J, Kawano Y, Nakamura K, Shimomura N, Ishikawa N, Arai T, Poon SS, Yamada N, Okada N, Wakiya T, Hayashida M, Saito T, Egami S, Hishikawa S, Ihara Y, Urahashi T, Mizuta K, Yasuda Y, Kawarasaki H, Takubo K. World J Surg. 2012; 36: 908-916
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Alcoholics show reduced telomere length in the oesophagus. Junko Aida, Akira Yokoyama, Naotaka Izumiyama-Shimomura, Ken-ichi Nakamura, Naoshi Ishikawa, Steven SS Poon, Mutsunori Fujiwara, Motoji Sawabe, Masaaki Matsuura, Tomio Arai, Kaiyo Takubo. J Pathol. 2011; 223: 410-416.
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Q-FISH analysis of telomere and chromosome instability in the oesophagus with and without squamous cell carcinoma in situ. Kaiyo Takubo, Masahiro Fujita, Naotaka Izumiyama, Ken-ichi Nakamura, Naoshi Ishikawa, Steven S Poon, Mutsunori Fujiwara, Motoji Sawabe, Masaaki Matsuura, Heike Grabsch, Tomio Arai1, Junko Aida. J Pathol. 2010; 221: 201-209.
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Telomere lengths in the oral epithelia with and without carcinoma. Junko Aida, Toshiyuki Izumo, Naotaka Shimomura, Ken-ichi Nakamura, Naoshi Ishikawa, Masaaki Matsuura, Steven SS Poon, Mutsunori Fujiwara, Motoji Sawabe, Tomio Arai, Kaiyo Takubo. Eur J Ca. 2010; 46: 430-438. (さらに…)
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